1-DAY ACUVUE^® MOIST

_{Packing solution contains boric acid and disodium tetraborate (sodium borate) to control the pH of the solution.}

_{# ClinicalTrials.gov is a website maintained by the NIH. The 11 clinical studies evaluated subjective comfort as a primary or secondary endpoint for 1- DAY^® ACUVUE MOIST brand family (spherical ONLY) contact lenses vs. competitors’ products. Review conducted as of April 30, 2024​.}

_{* Based on in-vitro data, clinical studies have not been done directly linking differences in lysozyme profile with specific clinical benefits.}

_{**All ACUVUE^® contact lenses have Class 1 or Class 2 UV-blocking to help provide protection against transmission of harmful UV radiation to the cornea and into the eye. UV-absorbing contact lenses are NOT substitutes for protective UV-absorbing eyewear such as UV-absorbing goggles or sunglasses because they do not completely cover the eye and surrounding area. UV transmission measured with -1.00 lens.}

_{§ In a year-long observational/surveillance registry that relied on patient reports of symptomatic adverse events that would have led them to seek clinical care, no symptomatic infiltrative events or serious adverse events were reported. These results should be considered in conjunction with other clinical results on the safety and efficacy of daily disposable etafilcon A contact lenses, which also generally show low rates of such events. Although no symptomatic infiltrative events were reported in this study, such events can and have occurred with daily disposable lenses, including 1-DAY ACUVUE^® MOIST, as noted in the product labelling.}

_{† This observational/surveillance registry relied on patient reports of symptomatic adverse events that led them to seek clinical care. These results should be considered in conjunction with other clinical results on the safety and efficacy of daily disposable etafilcon A contact lenses, which also generally show low rates of such events. Although no symptomatic infiltrative events were reported in this study, such events can and have occurred with daily disposable lenses, including 1-DAY ACUVUE^® MOIST, as noted in the product labelling.}

<sub>‡‡ Based on publicly available manufacturer information as of March 2020.
1. JJV Data on File 2021. Dual Action Technology and “Cushion of Moisture” Description for 1-DAY ACUVUE^® MOIST Brand Family of Contact Lenses.</sub>

_{2. JJV Data on File 2020. ACUVUE^® Brand - EYE-INSPIRED^TM Innovations.}

_{3. JJV Data on File, 2022. 1-DAY ACUVUE^® MOIST Claims from the TEMPO Observational Registry}

_{4. JJV Data on File 2020. 1-DAY ACUVUE^® MOIST Family Parameters Coverage}

_{5. JJV Data on File 2021. Technical attributes for 1-DAY ACUVUE^® MOIST with LACREON^® Technology.}

_{6. Omali NB, Subbaraman L, Heynen M, et al. Surface versus bulk activity of lysozyme deposited on hydrogel contact lens materials in vitro. Contact Lens Anterior Eye. 2018;41(4):329-334.doi: 10.1016/j.clae.2018.03.005.} 

^{Important Safety Information: ACUVUE® Contact Lenses are indicated for vision correction. As with any contact lenses, eye problems, including corneal ulcers, can develop. Some wearers may experience mild irritation, itching or discomfort. Contact lenses should not be used in case of eye infections or any other eye conditions, or in case of a systemic disease that may affect the eye. For detailed product information, including contraindications, precautions and adverse reactions, please consult the Instructions for Use available on Johnson & Johnson website www.e-IFU.com.}

^2024PP15399